Looking for a clinical trial that's right for you?
Find a TrialUCI Health, your source for clinical trials
UCI Health has Orange County’s largest clinical trials program, with 1,000-plus trials and over 3,000 patients enrolled in the past year. By participating in a clinical trial, you help shape the future of medicine. Help us discover and cure!
What are clinical trials?
Clinical trials evaluate the effects of new interventions on health.
Featured Trials
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study to Assess the Effectiveness of Tovinontrine
The purpose of this study is to evaluate the safety and effectiveness of Tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart failure with reduced ejection fraction.
Pelacarsen (TQJ230) in US Black/African and Hispanic populations with elevated Lp(a)
A Phase 3 study to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) in US Black/African American & Hispanic patient populations with elevated Lp(a) and established atherosclerotic cardiovascular disease.
A Study to Evaluate the Safety and Efficacy of KPI-012 in PCED
This clinical trial evaluates the safety and efficacy of KPI-012 ophthalmic solution in participants with persistent corneal epithelial defect (PCED).
Sangamo Fabry LTFU Study Protocol ST-920-LT01
A long-term follow-up of Fabry disease patients treated with ST-920, an rAAV2/6 gene therapy for alpha-galactosidase A.
A Phase II Study of ATR Inhibition in Advanced PD-(L)1-Refractory Merkel Cell Carcinoma
This clinical trial Phase 2 trial tests M1774 alone or with avelumab for patients not responding to anti-PD(L)1 therapy, comparing effectiveness and survival outcomes.
Repurposing Riluzole for Cancer-Related Cognitive Impairment: a Pilot Trial
A phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of Riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels of breast cancer survivors with cancer related cognitive impairment.
Learn more about clinical trials at UCI Health
Explore valuable resources and support for all aspects of clinical trials at UCI health
UCI Research News
UCI Health enrolls patient in first U.S. study of medical device for erectile dysfunction
UCI Health has opened the first U.S. clinical trial of a novel radiofrequency device designed to treat erectile dysfunction (ED). Men's health specialist Dr. Faysal A. Yafi is leading the study of Vertica®, a device, designed and manufactured by Ohh-Med Ltd.
2024 Cancer Center Scientific Retreat
This retreat on Friday, November 8, 2024 is open to CFCCC members, clinicians, DOT leaders, shared resource teams, CHOC partners, community equity board members, established community partners, MET trainees, staff, postdoctoral trainees, graduate students and undergraduate students in cancer-related research labs.
Advancing regenerative medicine therapies
University and community guests recently gathered to celebrate the 7,700 square-foot Good Manufacturing Practice facility’s grand opening in Hewitt Hall’s basement on the UC Irvine campus.