Prospect Eval of Efficacy of CMV-TCIP Direct Letermovir Prophylax after Allogen Hemato Cell Transpla

UCI Specialty Area: Cancer

Principal Investigator: Piyanuch Kongtim

Official Title: Prospective Evaluation of Efficacy of CMV-specific T Cell Immunity (CMV-TCIP) Directed Letermovir Prophylaxis after Allogeneic Hematopoietic Cell Transplantation

A Study On:

Hodgkin's Lymphoma

Leukemia other

Lymphoid Leukemia

Multiple Myeloma

Myeloid and Monocytic Leukemia

Non-Hodgkin's Lymphoma

Other Hematopoietic

Study Description

This is a phase 2, prospective cohort clinical trial evaluating the utilization of CMV T Cell Immunity Panel (CMV-TCIP) assay to guide the duration of primary CMV prophylaxis in CMV-seropositive recipients of allogeneic stem cell transplant or recipients receiving a stem cell graft from a CMV serology positive donor.

Eligibility

You can participate in this study if you satisfy the following criteria:

• Are at least 18 years of age or older

• Confirmed tested positive for CMV (either the donor or recipient) before undergoing Allogeneic Hematopoietic Cell Transplantation (AHCT).

You cannot participate in this study if you have any of the following criteria:

• Any uncontrolled infection

• Have a known or suspected hypersensitivity to letermovir

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University of California, Irvine - Study Information Sheet

UCI Center for Clinical Research Potential Participant Database

Lead Researcher
Maheswari Senthil, MD
UCI Center for Clinical Research

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Future Research Use
Researchers will use your information to conduct this study. Once the study is done using your information, we may share them with other researchers so they can use them for other studies in the future. We will not share your name or any other private identifiable information that would let the researchers know who you are. We will not ask you for additional permission to share this de-identified information

Data Retention - In accordance with UC Office of the President policy, information will be retained for 10 years after the end of the calendar year in which the research is completed.

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