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PhIIInotuzumab Ozogamicin Follow byBlinatumomab for Ph- Cd22+ B-LineageALL in OlderAdults or w/ R/R

UCI Specialty Area: Cancer
Principal Investigator: Deepa Jeyakumar
Official Title: Phase II Study of Inotuzumab Ozogamicin Followed by Blinatumomab for Ph-Negative Cd22-Positive B-Lineage Acute Lymphoblastic Leukemia in Newly Diagnosed Older Adults or Adults With Relapsed or Refractory Disease
A Study On:
Lymphoid Leukemia

Study Description

This phase II trial studies how well inotuzumab ozogamicin and blinatumomab work in treating patients with CD22-positive B-lineage acute lymphoblastic leukemia that is newly diagnosed, has come back, or does not respond to treatment. Immunotherapy with monoclonal antibodies, such as inotuzumab ozogamicin and blinatumomab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Eligibility

You can participate in this study if you

For cohort 1,

Age >= 60 years.

For cohort 2,

Age >= 18 years.

You cannot participate in this study if you

  • are pregnant or breast-feeding
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Privacy Policy

University of California, Irvine - Study Information Sheet

UCI Center for Clinical Research Potential Participant Database

Lead Researcher
Maheswari Senthil, MD
UCI Center for Clinical Research

In the instance of parental permission, “You” refers to “Your child.”

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