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PhIStudySafetyPharmacokineticsEfficacy BA3182 Bispecific (EPCAM)/CD3 Antibody Pa w/AdvAdenocarcinoma

UCI Specialty Area: Cancer
Principal Investigator: Jennifer Brooke Valerin
Official Title: An Open-Label, Multicenter, Phase I Study Evaluating the Safety, Pharmacokinetics, and Efficacy of BA3182, A Bispecific Epithelial Cell Adhesion Molecule (EPCAM)/CD3 Antibody, in Patients with Advanced Adenocarcinoma
A Study On:
Anus
Bones and Joints
Brain and Nervous System
Breast
Cervix
Colon
Corpus Uteri
Esophagus
Eye and Orbit
Ill-Defined Sites
Kaposis sarcoma
Kidney
Larynx
Lip Oral Cavity and Pharynx
Liver
Lung
Melanoma skin
Mycosis Fungoides
Other Digestive Organ
Other Endocrine System
Other Female Genital
Other Male Genital
Other Respiratory and Intrathoracic Organs
Other Skin
Other Urinary
Ovary
Pancreas
Prostate
Rectum
Small Intestine
Soft Tissue
Stomach
Thyroid
Unknown Sites
Urinary Bladder

Study Description

The objective of this study is to assess safety and efficacy of BA3182 in Advanced Adenocarcinoma

Eligibility

  • age 18 or older
  • Histologically or cytologically confirmed locally advanced unresectable or metastatic

adenocarcinoma and for whom available standard of care (SoC) therapy has failed or no

curative therapy is available or are not eligible, intolerant to, standard therapy.

  • Provide written informed consent (patient or legally acceptable representative)

-Incomplete recovery from the effects of major surgery or significant traumatic injury

before the first dose of study treatment.

  • Women who are pregnant or breastfeeding
  • Administered a live vaccine ≤ 4 weeks before enrollment.
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Privacy Policy

University of California, Irvine - Study Information Sheet

UCI Center for Clinical Research Potential Participant Database

Lead Researcher
Maheswari Senthil, MD
UCI Center for Clinical Research

In the instance of parental permission, “You” refers to “Your child.”

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