Outcomes w/ mpMRI Compared to Diagnostic TURBT in Pts w/ Suspected Muscle-Invasive Bladder Cancer

UCI Specialty Area: Cancer

Principal Investigator: Nataliya Mar

Official Title: Outcomes with Multi Parametric MRI (mpMRI) Compared to Diagnostic Transurethral Resection of Bladder Tumor (TURBT) in Patients with Suspected Muscle-Invasive Bladder Cancer - a Pilot Study

A Study On:

Urinary Bladder

Study Description

This is a pilot, single arm, prospective study that aims to validate the accuracy of the VI-RADS score obtained via multi-parametric magnetic resonance imaging (mpMRI) compared to pathologic cancer stage obtained via diagnostic transurethral bladder tumor resection (TURBT) as well as compare the clinical and quality of life outcomes between these diagnostic modalities in patients with suspected muscle-invasive bladder cancer (MIBC).

Eligibility

You can participate in this study if you

Are 18 years of age or older
Have suspected muscle-invasive bladder cancer (MIBC) determined by cystoscopy

You cannot participate in this study if you

Have prior TURBT within 120 days
Have prior therapy for bladder cancer within 120 days
Unable to tolerate mpMRI or associated contrast
Unable to tolerate TURBT or associated anesthesia
Unable to comply with study procedures
Do not consent for study follow up via phone call
Are pregnant or breastfeeding

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University of California, Irvine - Study Information Sheet

UCI Center for Clinical Research Potential Participant Database

Lead Researcher
Maheswari Senthil, MD
UCI Center for Clinical Research

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