Official Title: A Randomized Phase III Study Assessing the Efficacy and Safety of Olvi-Vec followed by Platinum-doublet Chemotherapy and Bevacizumab Compared with Platinum-doublet Chemotherapy and Bevacizumab in Women with Platinum-Resistant/Refractory Ovarian Cancer (OnPrime Study)
A Study On:
Cervix
Other Female Genital
Ovary
Study Description
A Randomized Phase 3 Study Assessing the Efficacy and Safety of Olvi-Vec followed by Platinum-doublet Chemotherapy and Bevacizumab Compared with Platinum-doublet Chemotherapy and Bevacizumab in Women with Platinum-Resistant/Refractory Ovarian Cancer
Eligibility
-Women >18 years old
History of histologically confirmed (from prior treatment) non-resectable ovarian, fallopian tube or primary peritoneal cancer.
-High-grade serous [including malignant mixed Mullerian tumor (MMMT) with metastasis that contains high grade epithelial carcinoma; FIGO grades 2 and 3 allowed], endometrioid, or clear-cell ovarian cancer.
-History of thromboembolic event within the prior 3 months.
-Pregnant or breast-feeding women.
-Smallpox vaccination within 1 year of study therapy.
Interested in Participating in this Trial?
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Privacy Policy
University of California, Irvine - Study Information Sheet
UCI Center for Clinical Research Potential Participant Database
Lead Researcher
Maheswari Senthil, MD
UCI Center for Clinical Research
In the instance of parental permission, “You” refers to “Your child.”
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