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PhIII Steroids+Tyrosine KI Induction w/Chemo or Blinatumomab for New Diagnose BCR-ABL+ ALL in Adults

UCI Specialty Area: Cancer
Principal Investigator: Deepa Jeyakumar
Official Title: A Phase III Randomized Trial of Steroids + Tyrosine Kinase Inhibitor Induction with Chemotherapy or Blinatumomab for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults
A Study On:
Lymphoid Leukemia

Study Description

This phase III trial compares the effect of usual treatment of chemotherapy and steroids and a tyrosine kinase inhibitor (TKI) to the same treatment plus blinatumomab. Blinatumomab is a Bi-specific T-Cell Engager ('BiTE') that may interfere with the ability of cancer cells to grow and spread. The information gained from this study may help researchers determine if combination therapy with steroids, TKIs, and blinatumomab work better than the standard of care.

Eligibility

You can participate in this study if you

  • are must be ≥ 18 and ≤ 75 years of age.

You cannot participate in this study if you

  • are pregnant or breast-feeding
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Privacy Policy

University of California, Irvine - Study Information Sheet

UCI Center for Clinical Research Potential Participant Database

Lead Researcher
Maheswari Senthil, MD
UCI Center for Clinical Research

In the instance of parental permission, “You” refers to “Your child.”

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