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VX-147 in Subjects Aged 12 Years and Older with APOL1-mediated Kidney Disease

UCI Specialty Area: Nephrology
Principal Investigator: Ekamol Tantisattamo
Official Title: A Phase 2/3 Adaptive, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of VX-147 in Adult and Pediatric Subjects With APOL1-mediated Proteinuric Kidney Disease
A Study On:
Kidney - Nephrology

Study Description

Eligibility

  1. APOL1 genotype of G1/G1, G2/G2, or G1/G2
  2. Proteinuric kidney disease

Key

  1. Solid organ or bone marrow transplant
  2. Uncontrolled hypertension
  3. History of diabetes mellitus
  4. Known underlying cause of kidney disease including but not limited to sickle cell disease

Other protocol defined Inclusion/Exclusion criteria apply.

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University of California, Irvine - Study Information Sheet

UCI Center for Clinical Research Potential Participant Database

Lead Researcher
Maheswari Senthil, MD
UCI Center for Clinical Research

In the instance of parental permission, “You” refers to “Your child.”

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